MGRA: Breakpoint graphs and ancestral genome reconstructions
MGRA (Multiple Genome Rearrangements and Ancestors)...for reconstruction of ancestor genomes and evolutionary history of extant genomes. It takes as an input a set...s such sequences for ancestral genomes at the internal nodes of the...n and deletions in addition to genome rearrangements and allows the...2530 days ago
2529 days ago
Web Apollo: a web-based genomic annotation editing platform
...technology is that there are more and more researchers sequencing new genomes. These researchers require tools to describe the functional features of their newly sequenced genomes. With Web Apollo researchers...2527 days ago
2525 days ago
Sequence - Evolution - Function; Computational Approaches in Comparative Genomics
...the computational approaches that play a critical role in the emerging new branch of biology known as fu...tential and limitations of computational and experimental approaches to genome analysis.2518 days ago
Meraculous: De Novo Genome Assembly with Short Paired-End Reads
We describe a new algorithm, meraculous, for whole genome assembly of deep paired-end sh...derived from the 15.4 megabase genome of the haploid yeast Pic...stipitis. More than 95% of the genome is recovered, with no errors;...rospects for assembling larger genomes are discussed.2425 days ago
QuorUM: An Error Corrector for Illumina Reads
Illumina Sequencing data can provide high coverage of a genome by relatively short (most often 100 bp to...n error in some read at every base in the genome. These errors make handling t...by correcting actual Illumina reads from genomes for which a reference assemb...2424 days ago
DFAST: a flexible prokaryotic genome annotation pipeline for faster genome publication
We developed a prokaryotic genome annotation pipeline, DFAST, that also supports genome submission to public seque...one command-line program. The new engine can annotate a typical-sized bacterial genome within 10 minutes, with rich...lso facilitate extensions for new functions and incorporation of n...2418 days ago
Genomicus: genome browser that enables users to navigate in genomes in several dimensions
Genomicus is a genome browser that enables users to navigate in genomes in several dimensions: linearly along chromosome axes, transv...gous and paralogous copies in all the other sequenced metazoan genomes. Moreover, Genomicus stores...2414 days ago
2412 days ago