Some useful Bioinformatics links
...thms/algorithms.html Measuring the distance between multiple sequence alignments | Bioinformatics | Oxford Aca...enomes/CustomGenomes.html Dot: Interactive dot plot for genome-genome alignments https://dnanexus.github.io/d...2246 days ago
Tools to Predict the Impact of Missense Variants !
...SIFT“Predicts whether an amino acid substitution affects protein function” GERP++“Identifies constrained elements in multiple alignments by quantifying substitution d...2207 days ago
Ancestral sequence reconstruction steps !
...amics of protein evolution. BEAST is the best way to predict the ancestral structure. but, I suggest following steps? 1- Alignments "Mafft - http://mafft.cb...2183 days ago
List of non-commercial NGS genotype-calling software
...Site frequency spectrum (SFS) estimation Samtools http://samtools.sourceforge.net/ Multi-sample Aligned reads Package for manipulation of NGS alignments, which includes a computation...2100 days ago