RNA Sequencing Helps Identify Functional Variants from GWAS
For Alzheimer’s and other complex disorders, mining the genome for disease-associated variants is no longer the obstacle. The challenge nowadays is figuring out how the identified loci relate to disease. As reported last month in Nature and its associated journals, advances in high-throughp...Tags: GWAS, RNA, Mining, Alzheimer
3824 days ago
Tags: CAUSEL, epigenome, genome, editing, pipeline, function, noncoding, GWAS, variants
1861 days ago
FUMA GWAS: Functional Mapping and Annotation of Genome-Wide Association Studies
FUMA is a platform that can be used to annotate, prioritize, visualize and interpret GWAS results. The SNP2GENE function takes GWAS summary statistics as an input, and provides extensive functional annotation for all SNPs in genomic areas identified by lead SNPs. The GENE...Tags: FUMA, GWAS, Functional, Mapping, Annotation, Genome-Wide, Association, Studies
1808 days ago
Tags: RAINBOWR, Reliable, Association, INference, R, SNP, GWAS
1535 days ago