Master Thesis: Trans-membrane topology prediction through Markov based decoders
Abstract: Background/Motivation: The dearth of structural information on alpha helical membrane protein (MPs) has hindered thus far the development of reliable knowledge –base...3957 days ago
Tools to Predict the Impact of Missense Variants !
...ectly predict the pathogenic character of new variants. Study of 10 tools on five datasets that such a comparative evaluation of these tools is hindered by two types of circularity:...2216 days ago
Tools to Predict the Impact of Missense Variants !
Prioritizing missense variants for further experimental investigation is a key challenge in current sequencing studies for exploring complex and Mendelian diseases. A large number of in silico tools have been employed for the task of pathogenicity prediction, including PolyPhen‐2, SIFT,...Tags: Evaluation, Tools, Predict, Missense, Variants, Hindered, Circularity
2216 days ago