Results for "genes"
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DarkHorse is a bioinformatic method for rapid, automated identification and ranking of phylogenetically atypical proteins on a genome-wide basis. It works by selecting potential ortholog matches from a reference database of amino acid sequences, then using these matches to calculate a lineag...Tags: Bioinformatics, HGT, Genes, Horizontal, Transfer, Method, Tools, DarkHorse
2868 days ago
What does phasing mean in biology/genetics?
Hi There, I recently came across a new term "phasing". What does it mean? I only know it means "genes separated by chromosome" only, can anyone please explain it for me. Thanks in advance.Tags: Genes, Separated, Chromosome, Biology, Phasing
2849 days ago
- Gene finding in eukaryotic genomes is notoriously difficult to automate. The task is to design a work flow with a minimal set of tools that would reach state-of-the-art performance across a wide range of species. GeneMark-ET is a gene prediction tool that incorporates RNA-Seq data into unsupervis...
Tags: Bioinformatics, Analysis, NGS, Braker, Annotation, Genes, Predictions, Genome
1945 days ago
- Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, t...
Tags: Bioinformatics, GeneBreak, Chromosome, Genome, NGS, Breakpoints, Genes
2148 days ago
- HybPiper was designed for targeted sequence capture, in which DNA sequencing libraries are enriched for gene regions of interest, especially for phylogenetics. HybPiper is a suite of Python scripts that wrap and connect bioinformatics tools in order to extract target sequences from high-throughpu...
Tags: Bioinformatics, Analysis, NGS, HybPiper, Genome, Network, Capture, Genes
2733 days ago
DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes
The DAGchainer software computes chains of syntenic genes found within complete genome sequences. As input, DAGchainer accepts a list of gene pairs with sequence homology along with their genome coordinates. Using a scoring function which accounts for the distance between neighboring genes on eac...Tags: Bioinformatics, DAGchainer, Computing, Chains, Syntenic, Genes, Genomes
2628 days ago
Enrichr: a comprehensive gene set enrichment analysis
Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gene set libraries available for analysis and down...Tags: Bioinformatics, Analysis, Enrichment, Enrichr, Web, Server, GO, Pathway, Genes, BED, Ontologies, Drug, Cell, Disease
2559 days ago
