Results for "sequencing"

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  • LoRMA: a tool for correcting sequencing errors in long reads such those produced by Pacific Biosciences sequencing machines

    LoRMA is a tool for correcting sequencing errors in long reads such those produced by Pacific Biosciences sequencing machines. Publication: L. Salmela, R. Walve, E. Rivals, and E. Ukkonen: Accurate selfcorrection of errors in long reads using de Bruijn graphs. Accepted to RECOMB-Seq 2016. ...

    Tags: Bioinformatics, LoRMA, Tool, Correcting, Errors, Reads, Sequencing

    2159 days ago

  • CovCal: Coverage / Read Count Calculator

    Coverage / Read Count Calculator Calculate how much sequencing you need to hit a target depth of coverage (or vice versa). Instructions: set the read length/configuration and genome size, then select what you want to calculate. Written by Stephen Turner, based on the Lander-Waterman formula, i...

    Tags: Bioinformatics, covcal, Tool, Coverage, Reads, Sequencing

    2159 days ago

  • GAM-NGS: genomic assemblies merger for next generation sequencing

    GAM-NGS is a tool able to merge two or more assemblies in order to improve contiguity and correctness. It can be used on all NGS-based assembly projects and it shows its full potential with multi-library Illumina-based projects. With more than 20 available assemblers it is hard to select the best...

    Tags: GAM-NGS, Genomic, Assemblies, Merger, Sequencing, NGS

    2537 days ago

  • GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies.

    GRASS (GeneRic ASsembly Scaffolder)-a novel algorithm for scaffolding second-generation sequencing assemblies capable of using diverse information sources. GRASS offers a mixed-integer programming formulation of the contig scaffolding problem, which combines contig order, distance and orientation...

    Tags: GRASS, Generic, Algorithm, Scaffolding, NGS, Sequencing, Assemblies

    2533 days ago

  • SIMBA: a web tool for managing bacterial genome assembly generated by Ion PGM sequencing technology

    SIMBA, SImple Manager for Bacterial Assemblies, is a Web interface for managing assembly projects of bacterial genomes. SIMBA was created to assist bioinformaticians to assemble bacterial genomes sequenced with NextGeneration Sequencing (NGS) platforms quickly, easily and effectively. SIMBA also ...

    Tags: SIMBA, Web, Tool, Bacterial, Genome, Assembly, Ion PGM, Sequencing

    2533 days ago

  • Grinder / Biogrinder - A versatile omics shotgun and amplicon sequencing read simulator

    Grinder is a versatile program to create random shotgun and amplicon sequence libraries based on DNA, RNA or proteic reference sequences provided in a FASTA file. Grinder can produce genomic, metagenomic, transcriptomic, metatranscriptomic, proteomic, metaproteomic shotgun and amplicon datasets...

    Tags: Grinder, Biogrinder, Versatile, Omics, Shotgun, Amplicon, Sequencing, Read, simulator

    2532 days ago

  • simNGS and simLibrary – Software for Simulating Next-Gen Sequencing Data

    simNGS is software for simulating observations from Illumina sequencing machines using the statistical models behind the AYB base-calling software. By default, observations only incorporate noise due to sequencing and do not incorporate effects from more esoteric sources of noise that may be pres...

    Tags: simNGS, simLibrary, Software, Simulating, Next-Gen, Sequencing, Simulation

    2344 days ago

  • Oxford Nanopore Sequencing, Hybrid Error Correction, and de novo Assembly of a Eukaryotic Genome

    Monitoring the progress of DNA molecules through a membrane pore has been postulated as a method for sequencing DNA for several decades. Recently, a nanopore-based sequencing instrument, the Oxford Nanopore MinION, has become available that we used for sequencing the S. cerevisiae genome. To make...

    Tags: Oxford, Nanopore, Sequencing, Hybrid, Error, Correction, de novo, Assembly, Eukaryotic, Genome

    2343 days ago

  • MetaSim A Sequencing Simulator for Genomics and Metagenomics.

    Our software can be used to generate collections of synthetic reads that reflect the diverse taxonomical composition of typical metagenome data sets. Based on a database of given genomes, the program allows the user to design a metagenome by specifying the number of genomes pr...

    Tags: MetaSim, Sequencing, Simulator, Genomics, Metagenomics

    2338 days ago

  • Jabba: Hybrid Error Correction for Long Sequencing Reads

    Jabba is a hybrid error correction tool to correct third generation (PacBio / ONT) sequencing data, using second generation (Illumina) data. Input Jabba takes as input a concatenated de Bruijn graph and a set of sequences: the de Bruijn graph should appear in fasta format with 1 entry per node...

    Tags: Jabba, Hybrid, Error, Correction, Long, Sequencing, Reads

    1975 days ago