Pattern Searching in a Single Genome
Pattern searching holds much importance for biologists , for the understanding of DNA ( and its functionality) can be more than a matter of satisfying curiosity , but also give answers to many issuess uchas medical conditions . However,there are a number of ways of searching with in a single chro...Tags: Bioinformatics, Genomics, Pattern, Chromosome, Study
2972 days ago
SATSUMA : Highly sensitive whole-genome synteny alignments.
Satsuma is a whole-genome synteny alignment program. It takes two genomes, computes alignments, and then keeps only the parts that are orthologous, i.e. following the conserved order and orientation of features, such as protein coding genes, non-coding genes, or neutral sequences. Satsuma does no...Tags: Bioinformatics, NGS, Sequence, Alignment, Synteny, Comparative genomics, Genomics
2905 days ago
MOSAIK: A Hash-Based Algorithm for Accurate Next-Generation Sequencing Short-Read Mapping
MOSAIK is a stable, sensitive and open-source program for mapping second and third-generation sequencing reads to a reference genome. Uniquely among current mapping tools, MOSAIK can align reads generated by all the major sequencing technologies, including Illumina, Applied Biosystems SOLiD, Roch...Tags: Bioinformatics, NGS, MOSAIK, Algorithm, Short-Read, Mapping, Genomics, Map, Tool
2897 days ago
Comparative genomics educational material and papers bookmarks
Alignment of the porcine genome against seven other mammalian genomes (Supplementary Information) identified homologous synteny blocks (HSBs). Using porcine HSBs and stringent filtering criteria, 192 pig-specific evolutionary breakpoint regions (EBRs) were located. The number of porcine EBRs is c...Tags: Bioinformatics, Comparative genomics, Genomics, Chromosome, Synteny, Evolution
2724 days ago
Method in Comparative genomics !!
We present methods for the automatic determination of genome correspondence. The algorithms enabled the automatic identification of orthologs for more than 90% of genes and intergenic regions across the four species despite the large number of duplicated genes in the yeast genome. The remaining a...Tags: Bioinformatics, Comparative genomics, Genomics, Chromosome, Analysis, Method, Evolution
2724 days ago
Tags: Bioinformatics, Comparative genomics, Genomics, Structure Variation, SV, NGS
2693 days ago
DIYA: a bacterial annotation pipeline for any genomics lab
DIY Genomics is an open source bioinformatics consortium intended to bring a collection of tools and libraries into the hands of small scale genomics labs for the process of sequence assembly and annotation. Projects include DIYA, MGAP, CRISPR, and DIYGV http://gmod.org/wiki/DiyaTags: DIYG, Genomics, Annotation, Bioinformatics, NGS
2491 days ago
Sequence - Evolution - Function; Computational Approaches in Comparative Genomics
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of t...Tags: Sequence, Evolution, Function, Computational, Approaches, Comparative, Genomics
2455 days ago
Computational Genomics: Applied Comparative Genomics
The primary goal of the course is for students to be grounded in theory and leave the course empowered to conduct independent genomic analyses. We will study the leading computational and quantitative approaches for comparing and analyzing genomes starting from raw sequencing data. The cours...Tags: Computational, Genomics, Applied, Comparative, Genomics
2340 days ago
MetaSim A Sequencing Simulator for Genomics and Metagenomics.
Our software can be used to generate collections of synthetic reads that reflect the diverse taxonomical composition of typical metagenome data sets. Based on a database of given genomes, the program allows the user to design a metagenome by specifying the number of genomes pr...Tags: MetaSim, Sequencing, Simulator, Genomics, Metagenomics
2334 days ago