Tags: Bioinformatics, NGS, Assembly, de novo, Sequence, Assembler, Heterozygous
2905 days ago
Tags: Bioinformatics, Analysis, NGS, Redundans, Assembly, Heterozygous, Genome
2794 days ago
Meraculous: Haplotype-sensitive Assembly of Highly Heterozygous genomes.
Meraculous is a whole genome assembler for Next Generation Sequencing data geared for large genomes. It is a hybrid k-mer/read-based assembler that capitalizes on the high accuracy of Illumina sequence by eschewing an explicit error correction step which we argue to be redundant with the assembly...Tags: Meraculous, Haplotype-sensitive, Assembly, Highly, Heterozygous, genomes, Meraculous-2D
2319 days ago
Purge Haplotigs: Pipeline to help with curating heterozygous diploid genome assemblies
Some parts of a genome may have a very high degree of heterozygosity. This causes contigs for both haplotypes of that part of the genome to be assembled as separate primary contigs, rather than as a contig and an associated haplotig. This can be an issue for downstream analysis whether you're wor...Tags: Purge, Haplotigs, Pipeline, curate, heterozygous, diploid, genome, assemblies
1957 days ago