Poonam Mahapatra
Bioinformatics Researcher
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Ka, Ks and Ka/Ks calculations
By Poonam Mahapatra 3006 days ago
http://longlab.uchicago.edu/?q=gKaKs
gKaKs is a codon-based genome-level Ka/Ks computation pipeline developed and based on programs from four widely used packages: BLAT, BLASTALL (including bl2seq, formatdb and fastacmd), PAML (including codeml and yn00) and KaKs_Calculator (including 10 substitution rate estimation methods). gKaKs can automatically detect and eliminate frameshift mutations and premature stop codons to compute the substitution rates (Ka, Ks and Ka/Ks) between a well-annotated genome and a non-annotated genome or even a poorly assembled scaffold dataset. It is especially useful for newly sequenced genomes that have not been well annotated.
Look for KaKs calculation:
https://github.com/fumba/kaks-calculator
