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  • Hifiasm: a haplotype-resolved assembler for accurate Hifi reads

Hifiasm: a haplotype-resolved assembler for accurate Hifi reads

https://github.com/chhylp123/hifiasm

Hifiasm is a fast haplotype-resolved de novo assembler for PacBio Hifi reads. It can assemble a human genome in several hours and works with the California redwood genome, one of the most complex genomes sequenced so far. Hifiasm can produce primary/alternate assemblies of quality competitive with the best assemblers. It also introduces a new graph binning algorithm and achieves the best haplotype-resolved assembly given trio data.