github.com - HiCanu, a significant modification of the Canu assembler designed to leverage the full potential of HiFi reads via homopolymer compression, overlap-based error correction, and aggressive false overlap filtering.
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The School of Biotechnology offers a curriculum that reflects the multidisciplinary nature of Biotechnology, integrating theoretical and applied science in undergraduate and graduate courses. The school has six departments with about 300 employees,...
www.broadinstitute.org - VICUNA is a de novo assembly program targeting populations with high mutation rates. It creates a single linear representation of the mixed population on which intra-host variants can be mapped. For clinical samples rich in...
The purpose of this cheat sheet is to introduce biologist and bioinformatician to the frequently used tools for NGS analysis as well as giving experience in writing one-liners.
File System ls — list items in current directory ls...
github.com - The pipeline can use information from scaffolded assemblies (for example from HiC or 10X Genomics), or even from diverged (~65-100 Mya) reference genomes for ordering the contigs and thus support the assembly process. This typically results in...
To remove all line ends (\n) from a Unix text file:
sed ':a;N;$!ba;s/\n//g' filename.txt > newfilename_oneline.txt
To get average for a column of numbers (here the second column $2):
awk '{ sum += $2; n++ } END { if (n > 0) print sum / n;...
The interaction between proteins and other molecules is fundamental to all biological functions. In this section we include tools that can assist in prediction of interaction sites on protein surface and tools for predicting the structure of the...
Here is a small tutorial on how to make best use of multiple processors for bioinformatics analysis. One best way is using perl threads and forks. Knowing how these threads and forks work is very important before implementing them. Getting to know...
Key Responsibilities
- Process and analyse metabolomic, transcriptional, genomics, proteomics
and any other kind of biological data.
- Interpret the data in the context of relevant biological literature to generate
actionable insights.
-...