Results for "Bioinformatics"
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Genetic differences among individuals reflect the combined effects of mutation, recombination, population history and natural selection. As a result, studies of natural variation can provide important insights into evolutionary and genetic mechanisms: as examples, DNA sequence conservation among ...Tags: Bioinformatics, Molly Przeworski, adaptation, recombination, population, selection
2996 days ago
- We are generally interested in the mechanisms of species origin from a molecular and ecological perspective. Particularly, we are interested in the role of sex chromosomes in speciation. Most of our research is done on birds and mammals. Currently, we focus our research on two hybridizing song bi...
Tags: Bioinformatics, Radka Reifová, adaptation, recombination, population, selection, Birds, Sex
2996 days ago
- The laboratory is focused on the discovery and analysis of structural variation (SVs) from genomic sequence data. As part of the 1000 Genomes Project and other endeavors, we have helped produce initial fine-scale maps using a variety of SV discovery approaches including: (i) paired-end mapping (o...
Tags: Bioinformatics, Gene, Epigenomics, Structure Variation, Deletion, Breakpoint, Chromosome
2986 days ago
- Evolutionary Dynamics and Population Genetics Natural selection and other evolutionary forces lead to particular patterns of evolutionary dynamics, and they leave characteristic signatures on the genetic variation within populations. We use a combination of theory and experiments to study the...
Tags: Bioinformatics, Evolution, Adaptation, Population, Selection, Michael Desai, Harvard
2930 days ago
- Lawley Lab are covered with a complex microbial community, known as our microbiota, which plays important roles in our physiology, immunity, metabolism and sustenance. Within the human gastrointestinal tract alone there are over 1,000 bacterial species, which amounts to approximately 10 times mor...
Tags: Bioinformatics, Evolution, Adaptation, Population, Sanger, Lawley, Laboratory
2912 days ago
- NAvin laboratory has pioneered the development of single cell sequencing technologies. They apply these tools to study complex biological processes that occur in human cancers including tumor initation, clonal evolution, invasion, metastasis and chemoresistance. These processes have previously ...
Tags: Bioinformatics, Cancers, Tumor, clonal evolution, Invasion, Metastasis, Chemoresistance
2902 days ago
- The Molecular Basis of Vertebrate Evolution. Naturally occurring species show spectacular differences in morphology, physiology, behavior, disease susceptibility, and life span. Although the genomes of many organisms have now been completely sequenced, Kingsley lab still know relatively little ab...
Tags: Bioinformatics, Evolution, Genomics, Vertebrate, Adaptation, Nature, Stanford
2887 days ago
- We are using a comparative genomics approach to better understand the structure, function and evolution of the human genome. Our group is one of the pioneers in the field of comparative genomics. We proposed the compact genome of the fugu (Takifugu rubripes) as a model vertebrate genome in 1993 (...
Tags: Bioinformatics, Comparative Genomics, Genomics
2687 days ago
- We are two groups of scientists doing frontier research in quantitative biology and biomedicine. The Bienko group is interested in exploring the fundamental design principles controlling how DNA is packed in the eukaryotic nucleus and its relation to gene expression regulation. The Crosetto group...
Tags: Nicola Crosetto, Magda Bienko, Lab, Chromosome, DNA, Bioinformatics, Histone, Omics, Tumor
2544 days ago
- We are a computational biology lab that develops novel methods for analysis of DNA and RNA sequences. Our research includes software for aligning and assembling RNA-seq data, whole-genome assembly, and microbiome analysis. We work closely with biomedical scientists to apply these methods to curre...
Tags: Bioinformatics, Steven, Salzberg, Lab, DNA, RNA, Assembly, Software, Mircobiome, NGS, Alignment, Genome
2541 days ago
