...segregation. In S. cerevisiae and in mammals, the majority of meiotic crossovers are formed through a highly...way. We are interested in charactering the role of these complexes in crossover formation and distribution am...
The bakers yeast, Saccharomyces cerevisiae is an ideal model organism to understand mechanisms of meiotic chromosome segregation. In S. cerevisiae and in mammals, the majority of meiotic crossovers are formed through a highly conserved MSH4p-MSH5p, MLH1p-MLH3p dependent pathway. We are interested...