2766 days ago
2710 days ago
1984 days ago
FSA: Fast Statistical Alignment
FSA is a probabilistic multiple sequence alignment algorithm wh...ding Methods for Optimization and Control of Multiple Alignment...roblems such as aligning thousands of sequences or megabase-lon...are subject to very different evolutionary constraints. FSA is capable...2658 days ago
DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes
The DAGchainer software computes chains of syntenic genes found...ng genes on each DNA molecule and the BLAST E-value score betwe...dered gene pairs are computed and reported. This algorithm can be used to mine large evolutionary conserved regions of genomes...s both the DAGchainer utility and a Java...2647 days ago
2606 days ago
CAR: Reconstructing Contiguous Regions of an Ancestral Genome
We describe a new method for predicting the ancestral order and orientation of those intervals f...31 bp. Analysis of the predicted evolutionary breakpoints in the h...cision, our theoretical analyses and computer simulations indicate that our...results are reasonably accurate and that t...2557 days ago
Mesquite: A modular system for evolutionary analysis
Mesquite is modular, extendible software for evolutionary biology, designed to help biologists organize and analyze comparative data about organisms. Its emphasis is on phylogenetic analysis, but some of its...2496 days ago
Mulan: MUltiple sequence Local AligNment and conservation visualization tool
Mulan performs multiple (2 or more) sequence alignments with an efficient and rapid "full local" alignment...t ensures a recapitulation of evolutionary sequence rearrangements (such as inversions and reshuffling) in any of the sp...graphical interface to align and visualize conservation profiles for ev...2494 days ago
MGRA: Breakpoint graphs and ancestral genome reconstructions
MGRA (Multiple Genome Rearrangements and Ancestors) is a tool for reconstruction of ancestor genomes and evolutionary history of extant ge...uences of genes (or synteny blocks) and produces such sequences for ancestral...sion 2 MGRA supports gene insertion and deleti...2489 days ago