BOL: Results for "HapSolo"

Results for "HapSolo"

- Jit@jit.aber
HapSolo: An optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding.
Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and secondary contigs are not properly identified,...
Tags: HapSolo, optimization, approach, remove, secondary, haplotigs, diploid, genome, assembly, scaffolding
1291 days ago
- Jit@jit.aber
HapSolo: An optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding
HapSolo, that identifies secondary contigs and defines a primary assembly based on multiple pairwise contig alignment metrics. HapSolo evaluates candidate primary assemblies using BUSCO scores and then distinguishes among candidate assemblies using a cost function. The cost function can be define...
Tags: HapSolo, optimization, approach, removing, secondary, haplotigs, diploid, genome, assembly, scaffolding
1097 days ago