Jit
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HapSolo: An optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding.
By Jit 1280 days ago
https://github.com/esolares/HapSolo
Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and secondary contigs are not properly identified, the primary assembly will overrepresent both the size and complexity of the genome, which complicates downstream analysis such as scaffolding.
