2754 days ago
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FSA: Fast Statistical Alignment
...alignment method makes FSA very robust: it can produce superior alignments of sets of homologous sequences which are subject to very different evolutionary constraints. FSA is capable...2646 days ago
DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes
...alue score between homologs, maximally scoring chains of ordered gene pairs are computed and reported. This algorithm can be used to mine large evolutionary conserved regions of genomes...2634 days ago
2593 days ago
CAR: Reconstructing Contiguous Regions of an Ancestral Genome
...the available human genome sequence data. The precision is further increased by mapping inversions as small as 31 bp. Analysis of the predicted evolutionary breakpoints in the human line...2545 days ago
Mesquite: A modular system for evolutionary analysis
Mesquite is modular, extendible software for evolutionary biology, designed to help biologists organize and analyze comparative data about organisms. Its emphasis is on phylogenetic anal...2484 days ago
Mulan: MUltiple sequence Local AligNment and conservation visualization tool
...performs multiple (2 or more) sequence alignments with an efficient and rapid "full local" alignment strategy that ensures a recapitulation of evolutionary sequence rearrangements (such...2482 days ago
MGRA: Breakpoint graphs and ancestral genome reconstructions
MGRA (Multiple Genome Rearrangements and Ancestors) is a tool for reconstruction of ancestor genomes and evolutionary history of extant genomes. It takes as an input a set of genomes re...2476 days ago