Results for "genes"
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Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, t...Tags: Bioinformatics, GeneBreak, Chromosome, Genome, NGS, Breakpoints, Genes
2151 days ago
- HybPiper was designed for targeted sequence capture, in which DNA sequencing libraries are enriched for gene regions of interest, especially for phylogenetics. HybPiper is a suite of Python scripts that wrap and connect bioinformatics tools in order to extract target sequences from high-throughpu...
Tags: Bioinformatics, Analysis, NGS, HybPiper, Genome, Network, Capture, Genes
2736 days ago
DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes
The DAGchainer software computes chains of syntenic genes found within complete genome sequences. As input, DAGchainer accepts a list of gene pairs with sequence homology along with their genome coordinates. Using a scoring function which accounts for the distance between neighboring genes on eac...Tags: Bioinformatics, DAGchainer, Computing, Chains, Syntenic, Genes, Genomes
2631 days ago
Enrichr: a comprehensive gene set enrichment analysis
Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gene set libraries available for analysis and down...Tags: Bioinformatics, Analysis, Enrichment, Enrichr, Web, Server, GO, Pathway, Genes, BED, Ontologies, Drug, Cell, Disease
2562 days ago
DeCoSTAR: Reconstructing the Ancestral Organization of Genes or Genomes Using Reconciled Phylogenies
DeCoSTAR computes adjacency evolutionary scenarios using a scoring scheme based on a weighted sum of adjacency gains and breakages. Solutions, both optimal and near-optimal, are sampled according to the Boltzmann–Gibbs distribution centered around parsimonious solutions, and statistical sup...Tags: DeCoSTAR, Reconstruction, Ancestral, Organization, Genes, Genomes, Reconciled, Phylogenies
1581 days ago
- KOALA (KEGG Orthology And Links Annotation) is KEGG's internal annotation tool for K number assignment of KEGG GENES using SSEARCH computation. BlastKOALA and GhostKOALA assign K numbers to the user's sequence data by BLAST and GHOSTX searches, respectively, against ...
Tags: KOALA, KEGG, annotation, tool, assignment, KEGG, GENES, SSEARCH, computation, Bacteria, Blast
1968 days ago
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