Bioinformatics tools to detect horizontal gene transfer (HGT) in genomes
...lex organisms it must enter the sequestered germline in order to be transmitted to offspring. Once there, it must not experience strong negative selection, despite potential for geneti...850 days ago
Tools to Predict the Impact of Missense Variants !
...as “rejected substitutions.” Rejected substitutions are a natural measure of constraint that reflects the strength of past purifying selection on the element” phyloP...2203 days ago
Tools for Protein-Protein Docking !
...annealing refinement . Filtering based on external data. ICM Global rigid search: Monte CarloEmpirical scoring function Clustering and selection of conformations. Refinement...2202 days ago