Horizontal gene transfer (HGT), the “non-sexual movement of genetic material between two organisms” , is relatively common in prokaryotes and single-celled eukaryotes, but a number of factors combine to make it far rarer in multicellular eukaryotes. In order for a eukaryotic species to gain a gene by HGT, foreign DNA must enter the host nucleus, integrate into the genome, and in more complex organisms it must enter the sequestered germline in order to be transmitted to offspring. Once there, it must not experience strong negative selection, despite potential for genetic incompatibility with the host genome and mismatch between the niche of the donor and the host. Over the longer term, foreign DNA may become “domesticated” in the recipient genome and provide novel function.
Following are the popular tool to detect HGT in genomes:
HGT detection / download & compile
HGT detection / download binary
HGT detection / download binary
HGT detection / download binary (!license!)
HGT detection / download & compile
HGT detection / download
HGT detection / download & install
HGT detection / git clone
HGT detection / download
HGT detection / download binary (!license!)
