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  • Deepbinner: a signal-level demultiplexer for Oxford Nanopore reads

Deepbinner: a signal-level demultiplexer for Oxford Nanopore reads

https://github.com/rrwick/Deepbinner

Deepbinner is a tool for demultiplexing barcoded Oxford Nanopore sequencing reads. It does this with a deep convolutional neural network classifier, using many of the architectural advances that have proven successful in image classification. Unlike other demultiplexers (e.g. Albacore and Porechop), Deepbinner identifies barcodes from the raw signal (a.k.a. squiggle) which gives it greater sensitivity and fewer unclassified reads.