There was a lot of buzz about Oxford Nanopore Technologies® is developing the GridION™ system and miniaturised MinION™ device. These are a new generation of electronic molecular analysis system for use in scientific research, personalised medicine, crop science, security/defence and more. The platform technology uses nanopores to analyse single molecules including DNA/RNA and proteins. With a broad patent portfolio, the Oxford Nanopore pipeline includes biological nanopores and solid-state nanopores.
Is this available, or still under trial mode?
https://www.nanoporetech.com/technology/the-minion-device-a-miniaturised-sensing-system/the-minion-device-a-miniaturised-sensing-system
Improved data analysis for the MinION nanopore sequencer
http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.3290.html
A complete bacterial genome assembled de novo using only nanopore sequencing data
Nanopore sequencing has made tremendrous progress- NEWS from London calling
Received news from a partner who participated in the London calling 2015 conference that Nanopore seq has made great progress including miniaturisation of sample preps and better quality and quantity of data- think several times before you purchase any old, I mean current generation NGS sequencers, particularly the AMC warranty contracts after an year that will cost you more than the sequences coming out of the current generation NGS boxes. Nanopores comes at 1/1000X prices while we all pay 5X and 10X for other boxes. I will post raw data and quality scores shortly.
Sequencing ultra-long DNA molecules with the Oxford Nanopore MinION
http://biorxiv.org/content/early/2015/05/20/019281.full-text.pdf+html
Additional tools for analyzing Oxford Nanopore minION data by John Urban
Researchers in Canada and the U.K. have for the first time sequenced and assembled de novo the full genome of a living organism, the bacteria Escherichia Coli, using Oxford Nanopore's MinIONTM device, a genome sequencer that can fit in the palm of your hand. http://www.sciencedaily.com/releases/2015/06/150615124724.htm
Yesterday, in his keynote address to the company’s user group conference in London, CTO Clive Brown announced the development of a new smartphone-powered nanopore sequencer, whimsically (and very Britishly) named ‘SmidgION’.
With 256 channels per flow cell, SmidgION will be smaller than the company’s existing MinION device, and is expected to come to market in early 2017. With SmidgION Oxford Nanopore are continuing to appeal to the field researcher, with potential applications in monitoring disease outbreaks, and real-time species identification in the fight against wildlife crime.
Prototype https://twitter.com/OmicsOmicsBlog/status/735921427694641153/photo/1
92% genome coverage of E. coli, average depth of 3.8x. But from just _43_ reads https://github.com/nickloman/massive-nanopore-silliness
