A new release of IgBLAST (1.17), the popular package for classifying and analyzing immunoglobulin and T cell receptor sequences, is now available on the web and from the FTP site. The updated package is better at identifying productive V gene sequences. We added a new field , “V frame shift”, to the IgBLAST output to indicate whether the V gene translation frame contains a frame-shift. We have also updated the definition of a productive V(D)J sequence to now exclude those with internal frame shifts.
See the new IgBLAST manual on the NCBI GitHub site for more information on setting up and running IgBLAST.
If you have any questions or concerns, please email us at blast-help@ncbi.nlm.nih.gov
