Manisha Mishra
A Bioinformatician
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AMStat: display statistics of large sequence files from next generation sequencing projects
By Neel 2675 days agosamstat.sourceforge.net - SAMStat is an efficient C program to quickly display statistics of large sequence files from next generation sequencing projects. When applied to SAM/BAM files all statistics are reported for unmapped, poorly and accurately mapped reads...MSAProbs - Parallel and accurate multiple sequence alignment
By Neel 2432 days agomsaprobs.sourceforge.net - MSAProbs is a well-established state-of-the-art multiple sequence alignment algorithm for protein sequences. The design of MSAProbs is based on a combination of pair hidden Markov models and partition functions to calculate posterior...RePS: Repeat-masked Phrap with scaffolding, a WGS sequence assembler
By Jit 2254 days agoftp.genomics.org.cn - RePS (Repeat-masked Phrap with scaffolding), a WGS sequence assembler, that explicitly identifies exact kmer repeats from the shotgun data and removes them prior to the assembly. The established software Phrap is used to compute meaningful error...LoFreq*: A sequence-quality aware, ultra-sensitive variant caller for NGS data
By BioStar 2209 days agocsb5.github.io - LoFreq* (i.e. LoFreq version 2) is a fast and sensitive variant-caller for inferring SNVs and indels from next-generation sequencing data. It makes full use of base-call qualities and other sources of errors inherent in sequencing (e.g. mapping or...VICUNA: a software tool that enables consensus assembly of ultra-deep sequence derived from diverse...
By biogeek 2020 days agowww.broadinstitute.org - VICUNA is a de novo assembly program targeting populations with high mutation rates. It creates a single linear representation of the mixed population on which intra-host variants can be mapped. For clinical samples rich in...ContigExtender: a new approach to improving de novo sequence assembly for viral metagenomics data
By LEGE 668 days agogithub.com - ContigExtender, was developed to extend contigs, complementing de novo assembly. ContigExtender employs a novel recursive Overlap Layout Candidates (r-OLC) strategy that explores multiple extending paths to achieve longer and highly accurate...GRIDSS: the Genomic Rearrangement IDentification Software Suite
By Rahul Nayak 2120 days agogithub.com - GRIDSS is a module software suite containing tools useful for the detection of genomic rearrangements. GRIDSS includes a genome-wide break-end assembler, as well as a structural variation caller for Illumina sequencing data. GRIDSS calls variants...NGS Platforms launched by BGI’s MGI Tech
By Jit 2613 days agoMGI, a subsidiary of global genomics leader BGI Group, announced pricing and its first early access customer for the new ultra high-throughput sequencer, MGISEQ-T7, saying it has driven down sequencing cost to $5 per gigabyte
