Computer simulation of genetic mechanism !!
...ve on the very diverse simulation tools that already exist, but focuses on mechanistic, dynamic models. Similarly, it is not meant to provide any coverage of the breadth of application...3003 days ago
Structural variation: the hidden genomic treasure
...ow be accurately assessed. Besides various methods of detection in next generation sequencing data (paired end mapping, split reads, and depth of coverage), array-based approaches have...2730 days ago
Software and Tools to detect structure variation with long reads !!
...e novo assembly resolves the most novel SV variants. 8-10X PacBio coverage of single genomes or trios re...using evidence from split-read alignments, high-mismatch regions, and coverage analysis. Please note the cur...2635 days ago
String graph based genome assembly software and tools !
...er) https://github.com/jts/sga Assembles large genomes from high coverage short read data. SGA is desig...nning FSG on multiple threads. Moreover, we have studied the effect of coverage rates on the running times....2356 days ago
BBTools for bioinformatician !
...36.59] rendomreads.sh gains the ability to simulate metagenomes. coverage=X will automatically set "reads" to a level that will give X average coverage (decimal point is allowed).me...2298 days ago
2161 days ago
Illumina based assembly pipeline steps !
...ce removal (iVar; amplicon data only) Duplicate read marking (picard; optional) Alignment-level QC (picard, SAMtools) Genome-wide and amplicon coverage QC plots (mosdepth) Choice o...905 days ago
39 days ago