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...ng (whole cDNA sequencing, RNA-seq), digital gene expression sequencing (Tag-Seq), ChIP-Seq, and so on. And there are many sequencing platform to generate sequece, as well know Sanger/...3286 days ago
Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-molecule and high-throughput sequence data to generate de novo assembled genomes that approach reference quality. h...3273 days ago
- ..., potentially tiling an entire large genome. DISCOVAR variant calling is under active development and transitioning to VCF. DISCOVAR de novo can generate de novo assemblies for both l...
2991 days ago
CANU: Assembling Large Genomes with Single-Molecule Sequencing and Locality Sensitive Hashing.
...ssues encountered. Canu is a hierachical assembly pipeline which runs in four steps: Detect overlaps in high-noise sequences using MHAP Generate corrected sequence consensus...2966 days ago
RCircos: an R package for Circos 2D track plots
...processing and graphic manipulation pipelines for presenting large-scale multi-sample genomic research data. It can also serve as a base tool to generate complex Circos images. More...2959 days ago
- ...analysis framework composed a number of integrated modules. These modules can be executed as a single program to generate a complete analysis report, or executed individually to generate specific charts and tables. G...
2934 days ago
- ...ploid genomes with SNPs and insertion/deletion (INDEL) polymorphisms, and simulate reads with uniform substitution sequencing errors. It does not generate INDEL sequencing errors, but...
2925 days ago
- ...romatin folding and affect gene expression levels. Genomic technologies for mapping interactions between DNA regions, e.g., ChIA-PET and HiC, can generate genome-wide maps of interacti...
2921 days ago
- ART is a set of simulation tools to generate synthetic next-generation sequencing reads. ART simulates sequen...ds in the FASTQ format, and alignments in the ALN format. ART can also generate alignments in the SAM alignme...
2792 days ago
- ...ntal reads and so-called pseudoreads and uses the resulting contigs to generate a modified reference sequence...n this way, it can very quickly, and at no additional sequencing cost, generate new, modified reference seque...
2770 days ago
