PEAR: a fast and accurate Illumina Paired-End reAd mergeR
...end read merger. It is fully parallelized and can run with as low as just a few kilobytes of memory. PEAR evaluates all possible paired-end read overlaps and without requiring the tar...2993 days ago
CANU: Assembling Large Genomes with Single-Molecule Sequencing and Locality Sensitive Hashing.
...rrently alpha level, feel free to use and report issues encountered. Canu is a hierachical assembly pipeline which runs in four steps: Detect overlaps in high-noise sequences using...2956 days ago
2736 days ago
Omega2: metagenome assembly pipeline
Omega found overlaps between reads using a prefix/suffix hash table. The overlap graph of reads was simplified by removing transitive edges and trimming short branches. Unitig...2533 days ago
Ra assembler - a de novo DNA assembler for third generation sequencing data
...vo assembly tool. Unlike other state-of-the-art assemblers, Ra does not have an error correction step. Instead, it relies on detecting overlaps using a very sensitive and sp...2362 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
...ler for long and noisy reads, such as those produced by PacBio and Oxford Nanopore Technologies. The algorithm uses an A-Bruijn graph to find the overlaps between reads and does not re...2235 days ago
BEAP: Blast Extension and Assembly Program
...fragment, often a EST or partial gene segment, as "primer", to recursively blast nucleotide databases in an attempt to obtain all sequences that overlaps, directly or indirectly, with...2197 days ago
minimap2: A versatile pairwise aligner for genomic and spliced nucleotide sequences
...cies asm-to-asm alignment ./minimap2 -x ava-pb reads.fa reads.fa > overlaps.paf # PacBio read overlap ./minimap2 -x ava-ont reads.fa reads.fa > overlaps.paf # Nanopore read overla...2188 days ago
GeneOverlap: An R package to test and visualize gene overlaps
Overlapping gene lists can reveal biological meanings and may lead to novel hypotheses. For example, histone modification is an important cellular mechanism that can pac...1998 days ago
NextDenovo: string graph-based de novo assembler for TGS long reads
...reads. It also contains a modified version of minimap2 for adapting input and output and producing more sensitive and accurate dovetail overlaps, and some useful utilities (s...1624 days ago