Ten recommendations for creating usable bioinformatics command line software
Bioinformatics software varies greatly in quality. In terms of usability, the command...products, waste less user’s time, and improve the quality of scientific analyses.3671 days ago
Swabs to Genomes: A Comprehensive Workflow
The sequencing, assembly, and basic analysis of microbial genomes, once a painstaking and expensive undertaking, has become almost trivial for research labs with access to standard mo...3608 days ago
3478 days ago
3468 days ago
InfoGenomeR: Integrative reconstruction of cancer genome karyotypes
InfoGenomeR is the Integrative Framework for Genome Reconstruction that uses a breakpoint graph to model the connec...type information to identify the optimal breakpoint graph representing cancer genomes....1149 days ago
Scaffolding of a bacterial genome using MinION nanopore sequencing
Second generation sequencing has revolutionized genomic studies. However, most genomes contain repeated DNA elements that are longer than the read lengths achievable with typical sequencers, so...3277 days ago
Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-molecule and high-throughput sequence data to generate de novo assembled genomes...3273 days ago
Directional dominance on stature and cognition in diverse human populations
Analysis of the genomes of >350,000 individuals revealed the existence of a small though measureable association between genome-wide homozygosity and some vital...3273 days ago
Simons Genome Diversity Project
Complete genome sequences from more than one hundred diverse human populations All genomes in the dataset were sequenced to at least 30x coverage using Illumina technology. The sequencing reads w...1145 days ago
Algorithms for DNA Sequencing (course offered each month)
"We will learn computational methods -- algorithms and data structures -- for analyzing DNA sequencing data. We wil...se Python to implement key algorithms and data structures and to analyze real genomes...3259 days ago