2001 days ago
molinspiration: broad range of cheminformatics software tools supporting molecule manipulation
Molinspiration offers broad range of cheminformatics software tools supporting mo...n and processing, including SMILES and SDfile conversion, normalization of molecules, generation...1989 days ago
SvABA: Genome-wide detection of structural variants and indels by local assembly
SvABA is a method for detecting structural variants in sequencing data using genome-wide local assembly. Under...ediately aligned to the reference with BWA-MEM and parsed to identify variants. Sequencing...1987 days ago
1987 days ago
nQuire: A statistical framework for ploidy estimation using NGS short-read data
nQuire implements a set of commands to estimate ploidy level of individuals from species, where recent polyploidi...nd intraspecific ploidy variation is observed. Specifically, nQuire uses next-generation sequencing...1978 days ago
MACSE: Multiple Alignment of Coding SEquences Accounting for Frameshifts and Stop Codons
MACSE aligns coding NT sequences with respect to their AA translation while allowing NT sequences to contain mult...ng undocumented frameshifts in public database sequences and in aligning next-generation sequencing...1960 days ago
HipSTR: Haplotype inference and phasing for Short Tandem Repeats
HipSTR was specifically developed to deal with these errors in the hopes of obtaining...models using an EM algorithm Mining candidate STR alleles from population-scale sequencing...1942 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
Flye is a de novo assembler for single molecule sequencing reads, such as those produced by PacBio and Oxford Nanopore Technologies. It is designed for a wide range of datasets, f...1916 days ago
jackalope: A swift, versatile phylogenomic and high-throughput sequencing simulator
jackalope simply and efficiently simulates (i) variants from reference genomes and (ii) reads f...ads from Pacific Biosciences These simulations include seque.... A swift, versatile phylogenomic and high-throughput sequencing...1802 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
Flye is a de novo assembler for single molecule sequencing reads, such as those produced by PacBio and Oxford Nanopore Technologies. It is designed for a wide range of datasets, f...1822 days ago