Tools to Predict the Impact of Missense Variants !
...and Mendelian diseases. A large number of in silico tools have b...as well as optimized methods of combining tool scores, such as Con...nts from the same protein occurring both in the datasets used for t...e functional impact of amino acid substitutions in proteins, such a...2261 days ago
Binding Site Prediction in Protein !
The interaction between proteins and other molecules is fundamental to all biological functions. In this s...Delaunay triangulation. Available also as PyMOL plugin Pocke...unctional regions in proteins by surface-mapping of phylogene...d degree of conservation metaPocketA meta server f...2260 days ago
Protein-Protein Interaction Sites Predictions !
...(PPIs) has a crucial role in biology, medicine and the pharmaceutical industry. PPIs can be investigated from two aspect...in a given PPI. Information about a protein’s interact...eraction sites. meta-PPISP is built on three individual web s...2260 days ago
Ligand Docking Tools and Software !
...nd/or popular docking tools. AutoDock Stochastic (GA)...ially flexible target ArgusLab Systematic Flexible ligandX...(GA)Flexible ligand and flexible targetAUTODOCK (empirical)...r characteristics of both the binding site and the ligand to...2260 days ago
Tools for Protein-Protein Docking !
...y dealing with molecular flexibility and conformational chang...complexes: 3D-Dock Suite Global rigid search: FFTShape comp...cs and VDWNone Escher NG Global rigid searchShape complemen...ealing refinement . Filtering based on external data. ...2260 days ago
2248 days ago
Creating conda environment for python2.7
TIP: By default, environments are installed into the envs directory in your conda dir...e myenv NOTE: Replace myenv with the environ...thon=3.4 scipy=0.15.0 astroid babel TIP: Install all t...You can add much more to the conda create comm...2248 days ago
Learning Python Programming - a bioinformatician perspective !
Python Programming is a general purpose progra...s rich set of utilities and libraries for data processing and...o-use features which supports big data processing. In this t...of points to recommend it to biologists and scientists speci...ynamically typed, so the variables types are defined automati...2240 days ago
Convert VCF to tab-deilimited table
...d with GATK : java -Xmx8g -jar GenomeAnalysisTK.jar \ -T VariantsToTable \ -R reference.fa \ -V...cf \ -F CHROM -F POS -F REF -F ALT -GF GT \ -o reference_genomes_GT.table multiple_sample.vcf should...2240 days ago
Frequent Paired-end reads (PE 2x100) mapping command lines
bowtie2 -x hs37m -X 650 -q -1 r1.fq -2 r2.fq -S r12.bowtie2.sam bwa aln hs37m.fa r1.fq > r1.sai &&...m.fa r2.fq > r2.sai \ && bwa sampe hs37m r1.sai r2.sai r...2.fq soap -D hs37m.fa.index -a r1.fq -b r2.fq -l 32 -g 3 -u dummy -2...2240 days ago