In a lot of my work in bioinformatics, I have been using hidden Markov models (HMMs). As a postdoc with David Hau...ere the group is working on methods for structure prediction from sequence. To read more...
The laboratory is focused on the discovery and analysis of structural variation (SVs)...ry approaches including: (i) paired-end mapping (or read pair analysis) based on abnormally mapped pairs of clone ends; (ii) read-depth...
They are using the latest DNA sequencing technology to read the genetic makeup of cancer cells within tumours in ever greater detail, teasing out patterns of evolution (evolutionary...