Sequence - Evolution - Function; Computational Approaches in Comparative Genomics
...nbsp;is an introduction to the computational approaches that play a critical role in...with an understanding of the principles and approaches of functional genomics and of...imitations of computational and experimental approaches to genome analysis.2467 days ago
RITA: Rapid identification of high-confidence taxonomic assignments for metagenomic data
...with compositional classifications from a Naive Bayes classifier, RITA is able to achieve very high accuracy on short reads. Unlike other hybrid approaches which combine these predictio...2354 days ago
Computational Genomics: Applied Comparative Genomics
...in theory and leave the course empowered to conduct independent genomic analyses. We will study the leading computational and quantitative approaches for comparing and analyzing g...2352 days ago
dipSPAdes: Assembler for Highly Polymorphic Diploid Genomes.
...ins challenging. As a result, there is a shortage of tools for assembling HP genomes from the next generation sequencing (NGS) data. The initial approaches to assembling HP genomes were...2330 days ago
Reference-free prediction of rearrangement breakpoint reads
.... Moreover, evaluation on a real prostate cancer dataset shows that the proposed method predicts more fusion transcripts correctly than previous approaches, and yet produces fewer false...2253 days ago
RNA-seq Analysis Workshop Course Materials
...- no genome assembly for the species of interest is available. In this case one would need to assemble the reads into transcripts using de novo approaches. This type of RNAseq is as mu...2136 days ago
ARC: pipeline which facilitates iterative, reference guided de novo assemblies
...curacy of results by only considering those reads which should assemble together. Reducing/removing reference bias as compared to mapping based approaches. The software is designed...2113 days ago
Hercules: a profile HMM-based hybrid error correction algorithm for long reads
...ection. In such cases researchers often combine both technologies and the more erroneous long reads are corrected using the short reads. Current approaches rely on various graph based a...2087 days ago
CoLoRMap: Correcting Long Reads by Mapping short reads
...re characterized by a high error rate, and assembling from long reads require a high depth of coverage. This motivates the development of hybrid approaches that leverage the high qualit...2087 days ago
2071 days ago