Flye: Fast and accurate de novo assembler for single molecule sequencing reads
Flye is a de novo assembler for long and noisy reads, such as those produced by PacBio and Oxford Nanopore Technologies. The algorithm uses an A-Brui...2206 days ago
PRICE (Paired-Read Iterative Contig Extension), a de novo genome assembler implemented in C++.
We are pleased to release PRICE (Paired-Read Iterative Contig Extension), a de nov...ds from a subset of the paired-read dataset, non-paired reads from sequencing technologies that provide non-paired data,...2169 days ago
HapCUT2: robust and accurate haplotype assembly for diverse sequencing technologies
...methods are specialized for specific read technologies or protocols, with sl...ed and accuracy across diverse sequencing technologies, including but not limited to...ng (>40x coverage-per-SNP) using above technologies combinations of the above technologies (e.g....2196 days ago
Hercules: a profile HMM-based hybrid error correction algorithm for long reads
Choosing whether to use second or third generation seq...ion. In such cases researchers often combine both technologies and the more erroneous long r...better and more accurate integration of these two technologies. Results: We designed and dev...2099 days ago
CoLoRMap: Correcting Long Reads by Mapping short reads
Second generation sequencing technologies paved the way to an exceptional increase in the number of sequenced genomes, both prokaryotic and eukaryotic. However, short reads are difficul...2099 days ago
LRCstats: a tool for evaluating long reads correction methods
LRCstats is an open-source pipeline for benchmarking D...than reads produced by next generation sequencing technologies, such as those produced by Il...ort reads outputted by next generation sequencing technologies to correct long reads.2097 days ago
2083 days ago
Wtdbg2: a de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore
Wtdbg2 is a de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore Technologies (ONT). It assembles raw reads...2039 days ago
COSINE: non-seeding method for mapping long noisy sequences
Third generation sequencing (TGS) are highly promising technologies but the long and noisy reads from TGS are difficult to align using existing algorithms. Here, we present COSINE, a conceptually new method designed specifically for aligning long reads contaminated by a high level of errors.2032 days ago
Referee: Genome assembly quality scores
Modern genome sequencing technologies provide a succint measure of quality at each position in every read, however all of this information is lost in the assembly process. Referee sum...2023 days ago