2981 days ago
2766 days ago
2147 days ago
BIMA V3: an aligner customized for mate pair library sequencing
...brary preparation protocol artifacts (biotin junction reads, paired-end read contamination, chimeras, etc.), and presence of structural variant breakpoints within reads increases mappin...2692 days ago
2655 days ago
CAR: Reconstructing Contiguous Regions of an Ancestral Genome
...human genome sequence data. The precision is further increased by mapping inversions as small as 31 bp. Analysis of the predicted evolutionary breakpoints in the human lineage confirms...2537 days ago
Reference-free prediction of rearrangement breakpoint reads
...oretical analyses of the number of neighboring reads. When applied to a dataset with a sequencing depth of 100×, it finds ∼88% of the breakpoints correctly with no false-posit...2243 days ago
NGMLR: long-read mapper designed to align PacBio or Oxford Nanopore
...e sequencing error and real genomic variations at the same time and makes it especially effective at more precisely identifying the position of breakpoints stemming from structural vari...2195 days ago
2147 days ago
2175 days ago