DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes
The DAGchainer software computes chains of syntenic genes found within complete genome sequences. As input, DAGchainer...ne pairs are computed and reported. This algorithm can be used to mine large evoluti...2627 days ago
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ERGO 2.0 Bioinformatics suites
ERGO 2.0 provides a systems biology informatics toolkit centered on comparative genomics to capture, query, and visualize sequenced genomes. Using Igenbio's proprietary algorit...2539 days ago
CAR: Reconstructing Contiguous Regions of an Ancestral Genome
We describe a new method for predicting the ancestral order and orientation of those intervals from their observed ad...increased by mapping inversions as small as 31 bp. Analysis of the predicted evoluti...2537 days ago
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Mesquite: A modular system for evolutionary analysis
Mesquite is modular, extendible software for evolutionary biology, designed to help biologists organize and analyze comparative data about organisms. Its emphasis is on phylogenetic analysis...2476 days ago
Mulan: MUltiple sequence Local AligNment and conservation visualization tool
Mulan performs multiple (2 or more) sequence alignments with an efficient and rapid "full local" alignment strategy that ensures a recapitulation of evoluti...2474 days ago
MGRA: Breakpoint graphs and ancestral genome reconstructions
MGRA (Multiple Genome Rearrangements and Ancestors) is a tool for reconstruction of ancestor genomes and evoluti...2469 days ago
Sequence - Evolution - Function; Computational Approaches in Comparative Genomics
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics....2457 days ago