Results for "Genome"
Tags
Validated a widely accessible approach that can be used to establish functional causality for noncoding sequence variants identified by GWASs. https://www.nature.com/articles/nm.3975Tags: CAUSEL, epigenome, genome, editing, pipeline, function, noncoding, GWAS, variants
1845 days ago
GMASS: a novel measure for genomeassembly structural similarity
The GMASS score is a novel measure for representing structural similarity between two assemblies. It will contribute to the understanding of assembly output and developing de novo assemblers. https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-019-2710-zTags: GMASS, novel, measure, genome, assembly, structural, similarity
1840 days ago
- The Rogers lab studies evolution of genome structure. We explore the ways that complex mutations like duplications, deletions, rearrangements, and retrogenes can create new genetic material. We study how these new mutations are important for adaptation. We are currently working on projects in Dro...
Tags: Rebekah, Rogers, evolution, genome, structure
1748 days ago
Apollo: First instantaneous, collaborative genomic annotation editor available on the Web
Apollo is a plug-in for the JBrowse Genome Viewer. In addition to genes and pseudogenes, users can annotate ncRNAs (snRNA, snoRNA, tRNA, rRNA), miRNAs, repeat regions, and transposable elements; each annotation type has its own configuration of the ‘Information Editor’. ...Tags: Apollo, collaborative, genomic, annotation, editor, Web, genome
1793 days ago
- Cogent is a tool that identifies gene families and reconstructs the coding genome using high-quality transcriptome data without a reference genome, and can be used to check assemblies for the presence of these known coding sequences. Cogent is a tool for reconstruct...
Tags: Cogent, tool, reconstruct, coding, genome, high-quality, full-length, transcriptome, sequences, genome, evaluation
1775 days ago
- Chromosome-level genome assembler combining multiple de novo assemblies https://github.com/jkimlab/IMAP
Tags: Integrative, Meta-Assembly, Pipeline, IMAP, Chromosome-level, genome, assembler, multiple, de novo, assemblies
1701 days ago
ALF--a simulation framework for genome evolution.
Artificial Life Framework (ALF) simulates a root genome into a number of related genomes. Result files include the resulting gene sequences, true tree and true MSAs. A description of ALF can be found in the following article: Daniel A Dalquen, Maria Anisimova, Gaston H Gonnet, Christophe Dessimo...Tags: ALF, simulation, framework, genome, evolution
1649 days ago
simuG: a general-purpose genome simulator
Simulated genomes with pre-defined and random genomic variants can be very useful for benchmarking genomic and bioinformatics analyses. Here we introduce simuG, a lightweight tool for simulating the full-spectrum of genomic variants (single nucleotide polymorphisms, Insertions/Deletions, copy num...Tags: simuG, general-purpose, genome, simulator
1612 days ago
- A Landmark in genomics, scientists have done something that hasn't been done ever. Scientists have reconstructed the genome of an ancient human who lived nearly 5,700 years ago in Southern Denmark from the birch pitch- an ancient tar-like substance. By sequencing the sample, researchers not onl...
Tags: reconstructed, genome, human, 5700, years, Denmark, ancient
1591 days ago
- We propose AirLift, a methodology and tool for comprehensively moving mappings and annotations from one genome to another similar genome while maintaining the accuracy of a full mapper.
Tags: AirLift, methodology, tool, moving, mappings, annotations, genome, similar, genome
1587 days ago
