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  • Cogent: a tool for reconstructing the coding genome using high-quality full-length transcriptome...

Cogent: a tool for reconstructing the coding genome using high-quality full-length transcriptome sequences.

https://github.com/Magdoll/Cogent
Cogent is a tool that identifies gene families and reconstructs the coding genome using high-quality transcriptome data without a reference genome, and can be used to check assemblies for the presence of these known coding sequences.
 

Cogent is a tool for reconstructing the coding genome using high-quality full-length transcriptome sequences. It is designed to be used on Iso-Seq data and in cases where there is no reference genome or the ref genome is highly incomplete.

See a recent presentation on Cogent being applied to the Cuttlefish Iso-Seq data.

Cogent preliminary draft paper (updated 2016Dec version)Supplementary

Please see wiki for details on usage.