IQ-TREE: Efficient software for phylogenomic inference
A fast and effective stochastic algorithm to infer phylogenetic trees by maximum likelihood. IQ-TREE compares favorably to RAxML and PhyML in terms of likelihoods with similar computing time IQ-TREE found higher likelihoods between 62.2% and 87.1% of the studied alignments, thus effici...Tags: IQ-TREE, Efficient, software, phylogenomic, inference
1897 days ago
HipSTR: Haplotype inference and phasing for Short Tandem Repeats
HipSTR was specifically developed to deal with these errors in the hopes of obtaining more robust STR genotypes. In particular, it accomplishes this by: Learning locus-specific PCR stutter models using an EM algorithm Mining candidate STR alleles from population-scale sequencing dat...Tags: HipSTR, Haplotype, inference, phasing, Short, Tandem, Repeats
1879 days ago
DADA2: Fast and accurate sample inference from amplicon data with single-nucleotide resolution
The DADA2 tutorial goes through a typical workflow for paired end Illumina Miseq data: raw amplicon sequencing data is processed into the table of exact amplicon sequence variants (ASVs) present in each sample. The DADA2 Workflow on Big Data goes through workflow op...Tags: DADA2, Fast, accurate, sample, inference, amplicon, data, single-nucleotide, resolution
1265 days ago
Orthoflow: workflow for phylogenetic inference of genome-scale datasets of protein-coding genes
Orthoflow is a workflow for phylogenetic inference of genome-scale datasets of protein-coding genes. Our goal was to make it straightforward to work from a combination of input sources including annotated contigs in Genbank format and FASTA files containing CDSs. It uses several state of the art ...Tags: Orthoflow, workflow, phylogenetic, inference, genome-scale, datasets, protein-coding, genes
68 days ago
Tags: RAINBOWR, Reliable, Association, INference, R, SNP, GWAS
1521 days ago
Smudgeplot: Inference of ploidy and heterozygosity structure using whole genome sequencing data
This tool extracts heterozygous kmer pairs from kmer count databases and performs gymnastics with them. We are able to disentangle genome structure by comparing the sum of kmer pair coverages (CovA + CovB) to their relative coverage (CovB / (CovA + CovB)). Such an approach also allows us to analy...Tags: Smudgeplot, Inference, ploidy, heterozygosity, structure, whole, genome, sequencing, data
794 days ago