CoLoRMap: Correcting Long Reads by Mapping short reads
Second generation sequencing technologies paved the way to an exceptional increase in the number of sequenced genomes, both prokaryotic and eukaryotic. However, short reads are difficult to assemble and often lead to highly fragmented assemblies. The recent developments in long reads sequencing m...Tags: CoLoRMap, Correcting, Long, Reads, Mapping, short, reads, pacbio
2081 days ago
LSC: Improving PacBio Long Read Accuracy by Short Read Alignment
Added Command line argument support. Multi-stage execution modes. Support for parallelization. Now execution proceeds in batches of long reads the size of which can be set by --long_read_batch_size N. Better compressed intermediate files. Added utilities folder. Added support for multiple ...Tags: LSC, Improve, correct, PacBio, Long, Read, Accuracy, Short, Read, Alignment
2064 days ago
HECIL: A Hybrid Error Correction Algorithm for Long Reads with Iterative Learning
HECIL—Hybrid Error Correction with Iterative Learning—a hybrid error correction framework that determines a correction policy for erroneous long reads, based on optimal combinations of decision weights obtained from short read alignments. HECIL’s core algorithm by introdu...Tags: HECIL, Hybrid, Error, Correction, Algorithm, Long, Reads, Iterative, Learning, longreads
1947 days ago
lordFAST: sensitive and Fast Alignment Search Tool for LOng noisy Read sequencing Data
lordFAST is a sensitive tool for mapping long reads with high error rates. lordFAST is specially designed for aligning reads from PacBio sequencing technology but provides the user the ability to change alignment parameters depending on the reads and application. lordFAST, a novel long-read mapp...Tags: lordFAST, sensitive, Fast, Alignment, Search, Tool, LOng, noisy, Read, sequencing, Data
1983 days ago