Tools to Predict the Impact of Missense Variants !
Prioritizing missense variants for further experimental investig...ive datasets that such a comparative evaluation of these tool...no acid substitution on the structure and function of a human...ynonymous single‐nucleotide variants, and noncoding variants&...2196 days ago
Binding Site Prediction in Protein !
The interaction between proteins and other molecules is fundamental to a...nd tools for predicting the structure of the intermolecular c...ENDO Identification protein interaction sites. It us...c, PASS, Q-SiteFinder and SURFNET2195 days ago
Protein-Protein Interaction Sites Predictions !
The study of Protein–Protein Interactions (PPIs) has a crucial role in biology, medicin...ic protein and the amino acid residues participating in a giv...y biological and clinical observations. Following are...C server Automated decision-tree approach to predicting prot...2195 days ago
Ligand Docking Tools and Software !
Ligand docking referred to cases where small molecule (“ligan...partial list of docking software, focusing on free (at least...empirical) FRED Systematic (RBD)Flexible ligandChemScore, P...ation which method would be more suitable in a specific conte...2195 days ago
Tools for Protein-Protein Docking !
Predicting the structure of protein–protein complexes using docking approaches is a difficult problem whose major challenges i...ic Integrated in VEGA GRAMM Global rigid search...MolFit Global rigid search: FFTShape complementarity...2195 days ago
2183 days ago
Creating conda environment for python2.7
TIP: By default, environments are installed into the envs directory in your conda directory...environment with a specific version of Python and multiple pa...bsp; ## Package Plan ## environment location: /home/urbe/an...################# | 100% ca-certificates 2018.03.07: ########...2183 days ago
Learning Python Programming - a bioinformatician perspective !
Python Programming is a general purpose programming language that is open source, flexible, powerful and eas...on and biopython is getting more popularity due to its easy-t...example which shows NGS data processing with the help of pyth...of) In general, following are some of the important featur...2176 days ago
Convert VCF to tab-deilimited table
Performed with GATK : java -Xmx8g -jar GenomeAnalysisTK.jar \ -T VariantsToTable \ -R reference.fa \ -V reference_genomes_GT.vcf \ -F CHROM -F POS -F REF -F...es_GT.table multiple_sample.vcf should also be converted to multiple_sample_GT.tabl...2175 days ago
Frequent Paired-end reads (PE 2x100) mapping command lines
bowtie2 -x hs37m -X 650 -q -1 r1.fq -2 r2.fq -S r12.bowtie2.sam bwa aln hs37m.fa r1.fq > r1.sai && bwa aln hs37...sai \ && bwa sampe hs37m r1.sai r2.sai r1.fq r2.fq >...2.fq > r12.gsnap.sam novoalign -r Random -o SAM -f r1.fq r2.fq...2175 days ago