...sceptibility genes for common diseases such as cancer, diabetes, hypertension, and cardiovascular disease, among others. The approa...will involve the development and application of new statistical me...actions associated with human disease.
Gene expression and protein expression patterns betwe...
We study the evolutionary biology of birds and relatives, combining field, museum and genomics approaches to understand the basis of avian diversity, evolution and behavior. Our guiding approac...ework for studying speciation, geographic variationand gen...
The focus of the Gerstein Lab is interpreting personal genomes, particularly in relation t...ng discipline of data science.
Personal Genome Variation: SVs
Human Genome Anno...seudogenes as Molecular Fossils
Protein Structure and Fun...
Welcome to our web-site compiling all the research-related activities of th...in Bioinformatics. We have a long-standing interest in protein structure prediction and structure-to-function relatio...peptide design, modeling of genetic variation, structure-based protein design and dif...
...f whole genome sequence data to identify genetic variation (primarily structural variation) and examine their potential functional impact in disease phenotypes. We are partic...ly resolved through modern sequencing approaches and which may exhibit interesting mec...
...on mathematical, statistical, and computational problems in evolutionary biology and human genetics. Long-term int...such as:
Human genetic variation
Inference of human...for genes that contribute to disease-susceptibility
More at http...
Raphael Lab research is focused on Bioinformatics and Computational Biology.
Current researc...ext-generation DNA sequencing, structural variation, genome rearrangements in cancer and evolution, and network analys...ve genomics, multiple sequence alignment, and mot...
The bakers yeast, Saccharomyces cerevisiae is an ideal model organism to understand mechanisms of meiotic chromos...plexes in crossover formation and distribution among all homolo...c background on mutation rate variation using S. cerevisiae as...udies are relevant for understanding...
Focusing on understanding the molecular mechanisms th...mRNA translation, localization and stability and role of non-cod...on, differentiation, apoptosis and senescence. Not surprisingly,...cer and neurological disorders and hold great potential as drug targets, disease markers, as well as therapeut...
A major focus of our lab is understanding the effects of genetic variation on molecular phenotypes and human disease. We develop methods for integrating diverse...cription, chromatin modifications, regulator binding, and their changes across multiple con...