DeCoSTAR - Detection of Co-evolution
DeCoSTAR is a software which aims at reconstructing ancestral gene or genome organizations, in the form of sets of neighborhood relations -adjacencies- between pairs of ancestral genes or gene domains.Ancestral genes or domains are deduced from reconciled gene trees in a context of birth, speciat...Tags: Bioinformatics, DeCoSTAR, Detection, Co-evolution, Reconstruction, Ancestral, Gene, Genome
2594 days ago
CAR: Reconstructing Contiguous Regions of an Ancestral Genome
We describe a new method for predicting the ancestral order and orientation of those intervals from their observed adjacencies in modern species. We combine the results from this method with data from chromosome painting experiments to produce a map of an early mammalian genome that accounts fo...Tags: Reconstruction, Contiguous, Regions, Ancestral, Genome, Bioinformatics, CAR
2560 days ago
ANGES: reconstructing ANcestral GEnomeS maps
This page contains the software ANGES 1.01, that aims at reconstucting ancestral genome maps from homologous markers in extant related genomes. Download Program, version 1.01 (July 10, 2012, documentation updated in August 2014) Examples with results (featured ancestors: boreoeutherian,...Tags: Reconstruction, Ancestral, Genomes, Maps, ANGES
2560 days ago
Tags: DESCHRAMBLER, Synteny, Ancestral, Reconstruction, Genome
2518 days ago
REGEN: Ancestral Genome Reconstruction for Bacteria
REGEN infers evolutionary events, including gene creation and deletion and replicon fission and fusion. The reconstruction can be performed by either a maximum parsimony or a maximum likelihood method. Gene content reconstruction is based on the concept of neighboring gene pairs. REGEN was design...Tags: REGEN, Ancestral, Genome, Reconstruction, Bacteria
2268 days ago
DUPCAR: Reconstructing Contiguous Ancestral Regions with Duplications
we propose a heuristic algorithm, called DUPCAR, for reconstructing ancestral genomic orders with duplications. The method starts from the order of genes in modern genomes and predicts predecessor and successor relationships in the ancestor. Then a greedy algorithm is used to reconstruct the ance...Tags: DUPCAR, Reconstructing, Contiguous, Ancestral, Regions, Duplications
2192 days ago
Ancestral Genomes: a resource for reconstructed ancestral genes and genomes across the tree of life
Ancestral Genomes (http://ancestralgenomes.org) is a resource for comprehensive reconstructions of these ‘fossil genomes’. Comprehensive sets of protein-coding genes have been reconstructed for 78 genomes of now-extinct species that were the common ancestors of extant species fr...Tags: Ancestral, Genomes, resource, reconstructed, genes, genomes, across, tree, life
2027 days ago
DeCoSTAR: Reconstructing the Ancestral Organization of Genes or Genomes Using Reconciled Phylogenies
DeCoSTAR computes adjacency evolutionary scenarios using a scoring scheme based on a weighted sum of adjacency gains and breakages. Solutions, both optimal and near-optimal, are sampled according to the Boltzmann–Gibbs distribution centered around parsimonious solutions, and statistical sup...Tags: DeCoSTAR, Reconstruction, Ancestral, Organization, Genes, Genomes, Reconciled, Phylogenies
1600 days ago
MGRA: Breakpoint graphs and ancestral genome reconstructions
MGRA (Multiple Genome Rearrangements and Ancestors) is a tool for reconstruction of ancestor genomes and evolutionary history of extant genomes. It takes as an input a set of genomes represented as sequences of genes (or synteny blocks) and produces such sequences for ancestral genomes at the in...Tags: MGRA, Breakpoint, graphs, ancestral, genome, reconstructions
2492 days ago
Genomicus: genome browser that enables users to navigate in genomes in several dimensions
Genomicus is a genome browser that enables users to navigate in genomes in several dimensions: linearly along chromosome axes, transversaly across different species, and chronologicaly along evolutionary time. Once a query gene has been entered, it is displayed in its genomic context in parallel...Tags: Genomicus, genome, browser, enables, navigate, genomes, several, dimensions, chromosome, evolution, ancestral, genome
812 days ago