Resolving the complexity of the human genome using single-molecule sequencing
The human genome is arguably the most complete mammalian reference assembly yet more than 160 euchromatic gaps remain and aspects of its structural variation remain poorly understood t...3217 days ago
Comparative genomics educational material and papers bookmarks
Alignment of the porcine genome against seven other mammalian genomes (Supplementary Information) identified homologous synteny blocks (HSBs). Using porcine HSBs and stringent filterin...2730 days ago
CABOG: Celera Assembler with Best Overlap Graph
...been a critical component of many genome sequencing projects. CABOG operates on small genomes such as bacterial as well as large genomes such as mammalian. CABOG is an extension of the...2544 days ago
CAR: Reconstructing Contiguous Regions of an Ancestral Genome
...ata from chromosome painting experiments to produce a map of an early mammalian genome that accounts for 96.8...published observations but disagrees with others. Although only a few mammalian genomes are currently sequenc...2541 days ago
Versatile genome assembly evaluation with QUAST-LG
QUAST-LG is an extension of QUAST intended for evaluating large-scale genome assemblies (up to mammalian-size). QUAST-LG is included in the QUAST package starting...1958 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
...s those produced by PacBio and Oxford Nanopore Technologies. It is designed for a wide range of datasets, from small bacterial projects to large mammalian-scale assemblies. The package...1856 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
...s those produced by PacBio and Oxford Nanopore Technologies. It is designed for a wide range of datasets, from small bacterial projects to large mammalian-scale assemblies. The package...1762 days ago
CSA: A high-throughput chromosome-scale assembly pipeline for vertebrate genomes
...mes (~1 Gbp) chromosome scale assemblies can be achieved within 12h on high-end Desktop computers (Intel i7, 12 CPU threads, 128 GB RAM). Larger mammalian genomes (~3Gbp) can be proces...1148 days ago