Evolutionary Dynamics and Population Genetics
Natural selection and other evolutionary forces lead to p...patterns of evolutionary dynamics, and they leave characteristic signatures on the genetic variatio...ns. We use a combination of theory and experiments to study the dynamics a...
The Molecular Basis of Vertebrate Evolution. Naturally occurrin...vior, disease susceptibility, and life span. Although the genom...isms have now been completely sequenced, Kingsley lab still know rel...little about the specific DNA sequence changes that underlie interes...
We are using a comparative genomics approach to better understand the structure, function and evolution of the human genome. Our group is one of the...l vertebrate genome in 1993 (Nature 366: 265-268, 1993) and determined its whole genome sequence...
The goal of the lab is to understand mammalian genomes using comparative genomic and epigenomic analyses. Areas of...: the evolution of regulatory sequences, the role of transposab...ng billions of DNA base pairs and interpreting how variation impacts basic biology and dis...
We investigate genome evolution across t...ing the incidence, mechanisms and rate of chromosome rearrangements, sequence structure of chromosome break...ts, modes of centromere shift and elimination, evolution of repetiti...uplication events, karyotypic variationand species radiations.
Mo...