HISAT2: a fast and sensitive alignment program for mapping next-generation sequencing reads
HISAT2 is a fast and sensitive alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as to a single reference genome). Based on an extension of BWT for graphs [Sirén et al. 2014], we designed and implemented a ...Tags: HISAT2, fast, sensitive, alignment, program, mapping, next-generation, sequencing, reads, tools
2182 days ago
Metassembler: merging and optimizing de novo genome assemblies
Metassembler combines multiple whole genome de novo assemblies into a combined consensus assembly using the best segments of the individual assemblies. Genome assembly projects typically run multiple algorithms in an attempt to find the single best assembly, although those assemblies often have ...Tags: Metassembler, merging, optimizing, de novo, genome, assemblies, tools
2182 days ago
Tags: EuGI, novel, genomic, islands, facilitate, horizontal, gene, transfer, detection, eukaryotes, tools
2178 days ago
Gap filling or Contigs extensions tools !
There are many tools to perform gap filling using Illumina short reads, for example "GapFiller: a de novo assembly approach to fill the gap within paired reads" or "Toward almost closed genomes with GapFiller". There are also some tools like GAPresolution that can help to perform local re-assembl...Tags: Gap, filling, Contigs, extensions, tools
2158 days ago
List of non-commercial NGS genotype-calling software
Meaningful analysis of next-generation sequencing (NGS) data, which are produced extensively by genetics and genomics studies, relies crucially on the accurate calling of SNPs and genotypes. Recently developed statistical methods both improve and quantify the considerable uncertainty associated w...Tags: List, non-commercial, NGS, genotype-calling, software, tools, snv
2089 days ago
Tags: DNA, Nucleotide, Counter, tools, scaf, chromatogram
2025 days ago
List of motif discovery tools !
In genetics, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. For proteins, a sequence motif is distinguished from a structural motif, a motif formed by the three-dimensional arrangement of amino ac...Tags: motif, discovery, tools, protein, dna
1986 days ago
molinspiration: broad range of cheminformatics software tools supporting molecule manipulation
Molinspiration offers broad range of cheminformatics software tools supporting molecule manipulation and processing, including SMILES and SDfile conversion, normalization of molecules, generation of tautomers, molecule fragmentation, calculation of various molecular properties needed in...Tags: molinspiration, broad, range, cheminformatics, software, tools, supporting, molecule, manipulation
1925 days ago