splitbam: splits a BAM by chromosomes
splitbam splits a BAM by chromosomes. Using the reference sequence dictionary (*.dict), it also creates some empty BAM files if no sam record was found for a chromosome. A pair of 'mock' SAM-Records can also be added to those empty BAMs to avoid some tools (like samtools) to crash. Usage ...Tags: Bioinformatics, Analysis, Assembly, Genome, Split, Reads
2613 days ago
How to check if fragmented set of assembly is alright ?
I assembled the genome, by fragmenting(split) the read data in TWO set. After assembling both sets, I am just wondering what to do the next? How to validate? Is that everything is going alright? I only use QUAST and it seems OK to me. Any other suggestions? Note: I assembled the genome w...Tags: NGS, Assembly, Fragmented, Split, Reads
2492 days ago
LAMSA: fast split read alignment with long approximate matches
LAMSA (Long Approximate Matches-based Split Aligner) is a novel split alignment approach with faster speed and good ability of handling SV events. It is well-suited to align long reads (over thousands of base-pairs). LAMSA takes takes the advantage of the rareness of SVs to implement a specifi...Tags: LAMSA, fast, split, read, alignment, long, approximate, matches
2173 days ago