Nataša Pržulj Lab's research involves applications of graph theory, mathematical modeling, and computational techniques to solving large-scale problems in computational and systems b...
Bioinformatics relevant research topics are:
genomic scale studies
endogenous mechanisms of mutations, germ line and somatic
computational aspects of immunology in cancer
sig...
...l and statistical methods to design and analyse novel experimental approaches in genetics and cell biology.
Future projects and goals
Large-scale systematic maps of gene-gene...
...thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; the...
"Our research focuses on understanding development, gene regulation, and epigenetics on a genome-wide scale, in the context of evolution. This involves the design and application of algorithms, statistics, and experimental approaches."
http://www.bccs.uni.no/units/cbu/research/rehmsmeier/
...iological systems through genome- and proteome-scale experimentation and analysis....cerevisiae, C. elegans or mouse.
Using genome-scale genotyping of natural polymor...otein interaction networks.
Integrating large-scale studies including phenotype,...
...tively attack the problems being addressed using a wide variety of approaches that include biochemistry, genetics, imaging, deep sequencing, large-scale RNAi screening and bioinforma...
...easily resolved through modern sequencing approaches and which may exhibit interesting mechanistic origins.
We are also interested in the large-scale integration of genomic, expre...
...tructural variation (SVs) from genomic sequence data. As part of the 1000 Genomes Project and other endeavors, we have helped produce initial fine-scale maps using a variety of SV di...
...ad to the manifestation of disease. We are inventing integrative methods for systems-level pathway modeling through integrative analysis of genome-scale datasets. We apply these appr...