The recent revolution in sequencing technologies has led to an exponential growth of sequence data. To tackle this ‘data deluge’, here Lawrence Berkeley National Laboratory introduce the BioPig sequence analysis toolkit as one of the solutions that scale to data and computation.
BioPig: a Hadoop-based analytic toolkit for large-scale sequence data http://bioinformatics.oxfordjournals.org/content/29/23/3014.short?rss=1
Lesser E-values and higher compatibility score :) ... then it will be real BLAST :P
This dream "A girl/boy with lesser E-values and higher compatibility score" is universal :)