BOL

Imagine looking through thousands of microbial genomes and discovering two genes that repeatedly appear together. The obvious conclusion is that they must somehow be connected—that perhaps they work together, participate in the same pathway, or...

A recent study by Webster and Chapman introduces Buscogeny, an open-source bioinformatics pipeline designed to make this process easier. The tool uses BUSCO (Benchmarking Universal Single-Copy Orthologs), which identifies conserved genes that are...

A recent study published in PLOS Computational Biology introduces REvolutionH-tl 2.0 (https://pypi.org/project/revolutionhtl/), a computational tool designed to help solve this mystery. The software analyzes protein sequences and identifies...

When scientists find an AMR gene, it shows that resistance exists. However, it does not always reveal where the gene is or what is around it. This genetic context can give important clues about how resistance genes work, change over time, and...

Imagine comparing humans and chimpanzees to discover which genes make us different. You have millions of RNA-sequencing reads—but there is a catch: the computer may align these reads more easily to one species' genome than the other.