BOL: proovread : large-scale high-accuracy PacBio correction through iterative short read consensus

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proovread : large-scale high-accuracy PacBio correction through iterative short read consensus

proovread : large-scale high-accuracy PacBio correction through iterative short read consensus

By Jit 2543 days ago

https://github.com/BioInf-Wuerzburg/proovread

proovread : large-scale high-accuracy PacBio correction through iterative short read consensus

outperforms PacBioToCA/LSC in terms of accuracy and contiguity/sensitivity (http://dx.doi.org/10.1093/bioinformatics/btu392)
is easy to install/run/configure
supports various types of dat
- HiSeq/MiSeq (100-500bp)
- Unitigs
- 454, ...

proovread maps high coverage data to pacbio reads (bwa mem, blasr, daligner) in multiple iterations.